The Canadian is into the third round of the Italian Open after her British opponent was forced to retire due to a lower back injury.
The Canadian needed three sets and over three hours to dispatch the Italian.
Felix Auger-Aliassime will meet Alexander Zverev in the Madrid quarter-finals.
The Scot managed to pull off the upset in three sets over the Canadian to reach the third round.
The Canadian was able to get by the Frenchman in straight sets in his opening match.
The American got by his Serbian opponent in straight sets to reach the second round in Madrid.
The Canadian dominated her American opponent in straight sets to register her first top 10 win since the 2019 US Open.
Bianca Andreescu survived a tough test from Alison Riske to reach the second round in Madrid.
Anett Kontaveit battled to victory over Angelique Kerber in Stuttgart.
Bianca Andreescu made a winning start to 2022 with a straight sets win over Jule Niemeier.
The Canadian will play her first match of 2022 against the German Jule Niemeier.
The US Open finalist overcame a mid-match blip to seal her place in the last 16.
The Canadian was pushed to three sets by the Spaniard but was able to pull through.
The players were tied at a set apiece when the American decided to call it quits due to dealing with an illness.
The Canadian has Cclaimed her second Tour title after coming through a three-set tussle with the Colombian.
The American was pushed to his limits in a three-set win over the Spaniard to reach the second round.
After losing to his Canadian rival last week, Rublev has turn the tables to win his first Tour title in almost a year.
The Canadian is into his second straight final after fighting past the Russian in two tight sets.
The Canadian controlled the game from start to finish en route to winning the trophy.
Sunday's final will see Auger-Aliassime bid to win his maiden Tour title. Meanwhile, Tsitsipas will be seeking to claim his first at a ATP 500 event.