There was a tense end to the fourth round match with Muguruza hitting out at her opponent.
The underdog has become the third qualifier in US Open history to reach the last eight of the men's singles tournament.
Elina Svitolina is into the last eight of the US Open after a dominating performance against Simona Halep.
After scoring one of the biggest wins of her career, the world No.43 paid a heartfelt tribute to 'one of her favourite people.'
Bianca Andreescu thrashed Greet Minnen to reach the last 16 at the US Open.
Naomi Osaka has admitted that she is unsure on when her next tournament will be after a third round exit at the US Open.
Felix Auger-Aliassime is into the last 16 of a grand slam for the fourth time in his last six appearances.
Leylah Fernandez stunned defending champion Naomi Osaka to reach the second week of a grand slam for the first time.
Simona Halep battled into the last 16 at the US Open.
Garbine Muguruza won the battle of the grand slam champions to reach the last 16 in New York.
Karolina Pliskova had her say on a thrilling late night victory over Amanda Anisimova at the US Open.
2019 champion Bianca Andreescu reached the last 32 at the US Open with a straight sets win over Lauren Davis.
The top seed said during her press conference journalists can 'write as much as they like' but she has complete confidence in her game.
Sloane Stephens talks about pressure and expectation after reaching the US Open third round.
Simona Halep is into the last 32 at the US Open for the first time in five years after comfortably beating Kristina Kucova.
The Slovakian former tennis star explains why she believes Raducanu is already technically better than her peer.
After her disappointments in New York in recent years, the 27-year-old is hoping to make up for it in 2021.
Belinda Bencic is still buzzing from her Olympic success in Tokyo as she takes her recent momentum to New York.
Bianca Andreescu came back from 4-2 down in the third set to beat Viktorija Golubic and extend her US Open winning streak to eight matches.
Ash Barty is into the second round of the US Open despite a problematic second set.